FIGURE

Fig. 2

ID

ZDB-FIG-110128-9

Publication

Haud et al., 2011 - rnaset2 mutant zebrafish model familial cystic leukoencephalopathy and reveal a role for RNase T2 in degrading ribosomal RNA

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Fig. 2

Subcellular localization of RNASET2. HEK293 cells were transfected with myc-epitope tagged WT RNASET2 (A) and the mutated version, RNASET2 C184R (B). Immunofluorescence for endoplasmic reticulum (PDI), Golgi, and late endosome (LAMP-1) markers show partial colocalization with WT RNASET2, suggesting that RNASET2 enters the secretory pathway. The mutated version colocalized completely with the PDI, suggesting ER retention. (Scale bar: 10 μm.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA