FIGURE

Fig. 2

ID

ZDB-FIG-100506-42

Publication

Nakano et al., 2010 - Biogenesis of GPI-anchored proteins is essential for surface expression of sodium channels in zebrafish Rohon-Beard neurons to respond to mechanosensory stimulation

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

Programmed cell death of RB neurons is diminished in mi310 mutants. (A) In a lateral view of a wild-type embryo at 2 dpf, anti-HuC labeled large cell bodies of RB neurons (green). Dashed lines represent somite boundaries. (B) A mutant embryo displayed a comparable number of HuC-positive cells at 2 dpf. (C) In wild type, RB neurons were eliminated by 4 dpf. (D) HuC-positive RB cells were observed in mutant larva at 4 dpf. (E) The number of RB neurons is significantly reduced between 2 and 4 dpf in wild type but not in mutants. (F) In a dorsal view of a wild-type embryo, some HuC-positive neurons (magenta) were also positive for TUNEL (green) at 2 dpf. (G) HuC-TUNEL double-positive neurons were rarely observed in mutants.

Expression Data

Gene:	elavl3
Antibody:	Ab1-elavl
Fish:	WT pigu^mi310/mi310
Anatomical Term:	Rohon-Beard neuron cell body
Stage Range:	Long-pec to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pigu^mi310/mi310
Observed In:	neuron apoptotic process Rohon-Beard neuron
Stage:	Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development