FIGURE

Fig. 3

ID

ZDB-FIG-090804-30

Publication

Tao et al., 2009 - The Integrator subunits function in hematopoiesis by modulating Smad/BMP signaling

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Fig. 3

Ints5 is required for erythrocyte differentiation. (A-C) May-Grunwald Giemsa staining shows normal red blood cells (RBCs) at various stages of differentiation at the indicated embryonic stages. (D-F) RBCs in embryos injected with control morpholinos (D), ints5 morpholinos (E), or co-injected with ints5 RNA and morpholinos (F) at 2 dpf. Arrows indicate the RBCs arrested at the basophilic erythroblast stage (E). (G-I) RBCs in embryos injected with control morpholinos (G), ints5 morpholinos (H), or co-injected with ints5 RNA and morpholinos (I) at 7 dpf. (J,K) Histograms showing the percentage of RBCs with normal (blue) or arrested (magenta) differentiation in injected embryos at 2 dpf (J) and 7 dpf (K). Scale bar: 10 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-ints5 + MO2-ints5
Knockdown Reagents:	MO1-ints5 MO2-ints5
Observed In:	erythrocyte maturation
Stage:	Prim-15

Phenotype Detail

Acknowledgments

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