FIGURE
Fig. 5
- ID
- ZDB-FIG-090710-45
- Publication
- Lightcap et al., 2009 - Interaction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish development
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Fig. 5
Overexpression of human Pak1 produces embryonic abnormalities in zebrafish that are contingent upon nuclear import of Pak1. (A) Images of zebrafish embryos at 4 dpf. Embryos were injected with either Pak1 WT-mRNA or one of the mRNA of the Pak1 nuclear import mutants (80 ng/μL). (B) Quantitative analysis of differential zebrafish body axis malformation at 4 dpf in embryos injected with either Pak1 WT-mRNA or one of the mRNA of the Pak1 nuclear import mutants. (C) Immunoblot analysis of lysates from zebrafish injected with either human Pak1-WT, NLSmut, or LC8mut mRNA. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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