FIGURE
Fig. 3
- ID
- ZDB-FIG-090710-43
- Publication
- Lightcap et al., 2009 - Interaction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish development
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Fig. 3
Pak1 nuclear import is contingent upon LC8 dimerization and is dynein independent. (A) Confocal microscopy images of MCF-7 cells transiently transfected with either the FKBP vector, Pak1 226–249, or Pak1 226–545 show either GFP-Pak1 construct is cytoplasmic in the absence of AP20187 and stained with DAPI to visualize nuclei. Scalebar shown is 10 microns. (B) Quantification of confocal images indicates an ∼5 fold increase in nuclear GFP over non-treated cells upon AP20187 treatment. Data quantified in the same manner as in Fig. 2B. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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