FIGURE

Fig. 5

ID

ZDB-FIG-080701-26

Publication

McFarland et al., 2008 - Hh and Wnt signaling regulate formation of olig2(+) neurons in the zebrafish cerebellum

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Fig. 5

Zebrafish cerebellum expresses wnt1 but not Hh pathway genes. All panels are lateral or dorsal views with anterior to the left. Dashed circles mark cerebellums. (A–C) Expression of shh was ventral to cerebellum. (D–F) Expression of ptc1 at 30 hpf was absent from cerebellum but by 48 hpf was present in the lower rhombic lip. (G, H) Expression of wnt1 at 30 hpf, red arrows mark transient wnt1 expression within the cerebellum and black arrows mark expression at the midbrain–hindbrain boundary. (I, J) By 48 hpf, wnt1 expression was no longer present within the cerebellum but persisted at the midbrain–hindbrain boundary. Scale bars represent 20 μm in all panels.

Expression Data

Genes:	ptch2 shha wnt1
Fish:	WT
Anatomical Terms:	cerebellum hindbrain midbrain midbrain hindbrain boundary
Stage Range:	Prim-15 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 318(1), McFarland, K.A., Topczewska, J.M., Weidinger, G., Dorsky, R.I., and Appel, B., Hh and Wnt signaling regulate formation of olig2(+) neurons in the zebrafish cerebellum, 162-171, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.