FIGURE

Fig. S1

ID

ZDB-FIG-080701-29

Publication

McFarland et al., 2008 - Hh and Wnt signaling regulate formation of olig2(+) neurons in the zebrafish cerebellum

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Fig. S1

atoh1a expression reveals cerebellum formation. All embryos shown are 48 hpf. Anterior is to the left in all panels, the first column depicts a lateral whole mount view, the second column a dorsal view. Black arrows point to the cerebellum. (A, B) Wild-type control embryos. Black dashed line indicates the width of the cerebellum (C, D) Embryos treated with CA at 6 hpf. From a dorsal view, the cerebellum appears thicker than in control embryos. Expression of atoh1a appears normal in transgenic embryos heat shocked to induce expression of Dkk1 at 30 hpf (E, F) and Df(LG01:lef1)^x8 mutant embryos (G, H). Scale bars represent 20 μm in all panels.

Expression Data

Gene:	atoh1a
Fish:	WT w32Tg/w32Tg Df(Chr01:lef1,msxb)x8/x8
Conditions:	chemical treatment: Cyclopamine heat shock
Anatomical Term:	cerebellum
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Condition:	chemical treatment: Cyclopamine
Observed In:	cerebellum
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 318(1), McFarland, K.A., Topczewska, J.M., Weidinger, G., Dorsky, R.I., and Appel, B., Hh and Wnt signaling regulate formation of olig2(+) neurons in the zebrafish cerebellum, 162-171, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.