ZFIN Image: McFarland et al., 2008, Fig. 5

Image

Figure Caption

Fig. 5 Zebrafish cerebellum expresses wnt1 but not Hh pathway genes. All panels are lateral or dorsal views with anterior to the left. Dashed circles mark cerebellums. (A–C) Expression of shh was ventral to cerebellum. (D–F) Expression of ptc1 at 30 hpf was absent from cerebellum but by 48 hpf was present in the lower rhombic lip. (G, H) Expression of wnt1 at 30 hpf, red arrows mark transient wnt1 expression within the cerebellum and black arrows mark expression at the midbrain–hindbrain boundary. (I, J) By 48 hpf, wnt1 expression was no longer present within the cerebellum but persisted at the midbrain–hindbrain boundary. Scale bars represent 20 μm in all panels.

Figure Data

Expression / Labeling details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 318(1), McFarland, K.A., Topczewska, J.M., Weidinger, G., Dorsky, R.I., and Appel, B., Hh and Wnt signaling regulate formation of olig2(+) neurons in the zebrafish cerebellum, 162-171, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.