FIGURE

Fig. 3

ID

ZDB-FIG-070921-6

Publication

Nambiar et al., 2007 - Zebrafish colgate/hdac1 functions in the non-canonical Wnt pathway during axial extension and in Wnt-independent branchiomotor neuron migration

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Fig. 3

Gross patterning of the hindbrain is unperturbed in col mutants. Hindbrain rhombomere patterning appears undisturbed in col mutant embryos (B, D and F) as compared to wildtype (A, C and E). Krox20 (red) labels r3 and r5 and valentino (blue) marks r5 and r6 (A and B). hoxb3 also marks r5 and r6 (C and D). fgf8 (blue) labels the mid-hindbrain boundary and krox20 (red) marks r3 and r5 showing that gross development between the mid-hindbrain boundary and r3 in the hindbrain also appears normal in col mutant embryos (F as compared to E). RMO44 labels reticulospinal neurons (G and H). The patterning of this neuronal population is relatively unperturbed in col mutants although overall neuronal numbers appear to be reduced (see Section 2).

Expression Data

Genes:	egr2b fgf8a hoxb3a mafba
Fish:	WT hdac1^b382/b382
Anatomical Terms:	midbrain hindbrain boundary neural keel rhombomere 3 rhombomere 5 rhombomere 6
Stage:	10-13 somites

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Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Mechanisms of Development, 124(9-10), Nambiar, R.M., Ignatius, M.S., and Henion, P.D., Zebrafish colgate/hdac1 functions in the non-canonical Wnt pathway during axial extension and in Wnt-independent branchiomotor neuron migration, 682-698, Copyright (2007) with permission from Elsevier. Full text @ Mech. Dev.