FIGURE

Fig. 4

ID
ZDB-FIG-070810-14
Publication
Chong et al., 2007 - The chemokine, Sdf-1, and its receptor, Cxcr4, are required for formation of muscle in zebrafish
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Fig. 4

Slow muscle migration defects in cxcr4a and sdf1a morphants. Confocal images of embryos stained for slow myosin using F59 antibody. Dorsal (A-C;G-I) and lateral (D-F) views of embryonic trunk between the fourth and tenth somites. (A-C) Adaxial cells in cxcr4a and sdf1a morphants are identical to that in controls, 19 h. (D-I) Embryos at 25 h. (D-F) Z-stacked images of ten frames. (G-I) Z-stacked images of two frames. (D) Distinct and properly aligned slow fibers are seen in control embryo. (E,F) Gaps are seen in myotomes of representative cxcr4a and sdf1a morphant, indicated by white arrows. (G) Control. (H,I) Loss of fiber at the superficial layer and misrouted slow muscle, indicated by white arrows in representative cxcr4a and sdf1a morphant respectively. Other misrouted slow fibers in morphants are in different planes (data not shown).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage: Prim-5

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.