FIGURE
Fig. 5
Fig. 5
Expression pattern of atp7a via in situ hybridization Anterior (a), posterior (p), and dorsal (d) are as indicated. A) atp7a message is present in all cells at 3 hpf. B) Staining is specific, as a sense-control probe does not show staining. C) At 8 somites, atp7a is expressed most abundantly in the notochord and is expressed ubiquitously at lower levels. D and E) Sectioning at 24 hpf reveals staining along the ventricle (D) (arrowhead) and in the distal notochord (E) (arrow). F) In situ analysis of atp7b reveals expression in the liver (arrowhead) in a 5 dpf embryo as shown in this dorsal view. |
Expression Data
| Genes: | |
|---|---|
| Fish: | |
| Anatomical Terms: | |
| Stage Range: | 1k-cell to Day 5 |
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Reprinted from Cell Metabolism, 4(2), Mendelsohn, B.A., Yin, C., Johnson, S.L., Wilm, T.P., Solnica-Krezel, L., and Gitlin, J.D., Atp7a determines a hierarchy of copper metabolism essential for notochord development, 155-162, Copyright (2006) with permission from Elsevier. Full text @ Cell Metab.