FIGURE

Fig. 2

ID

ZDB-FIG-061206-7

Publication

Lee et al., 2006 - Canonical Wnt signaling through Lef1 is required for hypothalamic neurogenesis

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Fig. 2

lef1 is co-expressed with proneural and neuronal markers in the posterior hypothalamus. White circles outline posterior hypothalamus and inset panels show lef1 mRNA expression from Fast Red fluorescence. Lines in whole-mount images show plane of corresponding cross-sections on the right. In cross-sections, black ovals outline posterior hypothalamus. (A,B) At 19 hpf, sox3 (blue) is not co-expressed with lef1 (red) in the posterior hypothalamus. (C,D) At 24 hpf, zash1a (blue) is not co-expressed with lef1 (red) in the posterior hypothalamus. (E-H) By 30 hpf, sox3 and zash1a are co-expressed with lef1 in both medial progenitors and lateral postmitotic neurons of the posterior hypothalamus. (I-L) By contrast, dlx2 and isl1 are co-expressed only with lef1 in lateral postmitotic neurons.

Expression Data

Genes:	ascl1a dlx2a isl1a lef1 sox3
Fish:	WT
Anatomical Terms:	diencephalon forebrain hypothalamus
Stage Range:	20-25 somites to Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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