FIGURE

Fig. 8

ID

ZDB-FIG-240306-53

Publication

Dennhag et al., 2024 - fhl2b mediates extraocular muscle protection in zebrafish models of muscular dystrophies and its ectopic expression ameliorates affected body muscles

Other Figures

All Figure Page

Back to All Figure Page

Fig. 8

Model for fhl2b mediated rescue of muscular dystrophy.

fhl2b is upregulated and protects EOMs from muscular dystrophy conditions. dmd^−/− larvae overexpressing fhl2b survive for extended amounts of time due to improved muscle integrity with fewer myofiber detachments and breaks, improved axon and NMJ stability, and accelerated myofiber regeneration. Schematic images were adapted from https://www.biorender.com.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.