FIGURE SUMMARY
Title

CCN1 interlinks integrin and Hippo pathway to autoregulate tip cell activity

Authors
Park, M.H., Kim, A.K., Manandhar, S., Oh, S.Y., Jang, G.H., Kang, L., Lee, D.W., Hyeon, D.Y., Lee, S.H., Lee, H.E., Huh, T.L., Suh, S.H., Hwang, D., Byun, K., Park, H.C., Lee, Y.M.
Source
Full text @ Elife

Arterio-venous identity was altered in <italic>ccn1</italic> MO embryos.

In situ hybridization of Notch-1b and Flt-4 was performed at 32 hpf in control and ccn1 MO-injected zebrafish embryos. The expression of Notch-1b was normally in neural tube (NT), DA and ISV and Flt-4 was in PCV. However, in the ccn1 morphants, Notch-1b expression was markedly decreased at DA and ISV and Flt-4, venous markers, was expressed both in DA and PCV. Scale bar = 50 µm.

Arterio-venous identity was altered in <italic>ccn1</italic> MO embryos.

In situ hybridization of Notch-1b and Flt-4 was performed at 32 hpf in control and ccn1 MO-injected zebrafish embryos. The expression of Notch-1b was normally in neural tube (NT), DA and ISV and Flt-4 was in PCV. However, in the ccn1 morphants, Notch-1b expression was markedly decreased at DA and ISV and Flt-4, venous markers, was expressed both in DA and PCV. Scale bar = 50 µm.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife