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Phenotype Figure Summary
Marker:
nkx2.7
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Colombo
et al.
, 2017
Fig. 4
nkx2.7
vu413/vu413
atrium
isl1a
expression increased distribution, abnormal
atrium
isl1a
expression mislocalised, abnormal
atrium
isl1a
expression spatial pattern, abnormal
Fig. 5
nkx2.7
vu413/vu413
; fb7Tg
atrium
isl1a
expression increased distribution, abnormal
atrium
isl1a
expression mislocalised, abnormal
atrium
isl1a
expression spatial pattern, abnormal
Fig. 7
nkx2.7
vu413/vu413
myocardium
bmp4
expression increased amount, abnormal
myocardium
hcn4
expression increased amount, abnormal
myocardium
hcn4
expression increased distribution, abnormal
myocardium
hcn4
expression spatial pattern, abnormal
myocardium
tbx2b
expression increased amount, abnormal
myocardium
tbx2b
expression increased distribution, abnormal
myocardium
tbx2b
expression spatial pattern, abnormal
Fig. 8
nkx2.7
vu413/vu413
myocardium
bmp4
expression increased amount, abnormal
myocardium
bmp4
expression increased distribution, abnormal
myocardium
bmp4
expression spatial pattern, abnormal
Targoff
et al.
, 2013
Fig. 3
WT + MO1-nkx2.7
heart morphology, abnormal
Fig. 4
nkx2.7
vu413/vu413
heart morphology, abnormal
Fig. 5
WT + MO1-nkx2.7
atrial myocardium cardiac muscle cell loose, abnormal
atrial myocardium disorganized, abnormal
atrial myocardium increased width, abnormal
ventricular myocardium cardiac muscle cell condensed, abnormal
ventricular myocardium decreased width, abnormal
ventricular myocardium shortened, abnormal
Fig. 6
WT + MO1-nkx2.7
atrial myocardium increased size, abnormal
atrial myocardium swollen, abnormal
ventricular myocardium decreased size, abnormal
ventricular myocardium increased width, abnormal
Tu
et al.
, 2009
Fig. 1
twu34Tg + MO3-nkx2.7
heart development disrupted, abnormal
heart looping disrupted, abnormal
Fig. 2
AB + MO3-nkx2.7
cardiac ventricle morphology, abnormal
Fig. 5
AB + MO3-nkx2.7
cardiac muscle cell differentiation disrupted, abnormal
heart development disrupted, abnormal
heart morphogenesis disrupted, abnormal
Fig. 6
AB + MO3-nkx2.7
cardiac muscle cell differentiation disrupted, abnormal
heart development disrupted, abnormal
heart morphogenesis disrupted, abnormal
text only
twu34Tg + MO3-nkx2.7
cardiac ventricle hypotrophic, abnormal
heart contraction arrhythmic, abnormal
heart development disrupted, abnormal
heart looping disrupted, abnormal
heart morphology, abnormal
pericardium edematous, abnormal
Targoff
et al.
, 2008
Fig. 1
WT + MO1-nkx2.7
atrium shape, abnormal
cardiac ventricle decreased size, abnormal
text only
WT + MO2-nkx2.7
atrium shape, abnormal
cardiac ventricle decreased size, abnormal
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