FIGURE

Fig. 2

ID

ZDB-FIG-090127-70

Publication

Tu et al., 2009 - Nkx2.7 and Nkx2.5 function redundantly and are required for cardiac morphogenesis of zebrafish embryos

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Fig. 2

Nkx2.5 was overexpressed in the Nkx2.7-knockdown embryos.

Nine nanograms of Nkx2.7-MO were injected into one-cell stage of embryos. Nkx2.5 was expressed predominantly in ventricle (v) and weakly in atrium (a) of wild-type (WT) embryos at 48 hpf (A), but only minimally and weakly in ventricle at 72 hpf (C). However, the Nkx2.7-MO-injected embryos retained robust Nkx2.5 expression in ventricle both at 48 and 72 hpf (B and D). The embryonic stages were as indicated, and embryos were observed ventrally. v: ventricle; a: atrium.

Expression Data

Gene:	nkx2.5
Fish:	AB AB + MO3-nkx2.7
Knockdown Reagent:	MO3-nkx2.7
Anatomical Terms:	atrium cardiac ventricle
Stage Range:	Long-pec to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO3-nkx2.7
Knockdown Reagent:	MO3-nkx2.7
Observed In:	cardiac ventricle
Stage Range:	Long-pec to Protruding-mouth

Phenotype Detail

Acknowledgments

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