Publication	Data		Fish	Anatomy
Nguyen et al., 2023	Fig. 6.		tfap2ats213/ts213 (AB) ,   tfap2ats213/ts213; y1Tg (AB)	ethmoid cartilage cartilaginous projection mislocalised, abnormal ethmoid cartilage medial side split, abnormal eye cartilage tissue mislocalised, abnormal mouth medial region alx3 expression decreased distribution, abnormal mouth superior side alx3 expression decreased distribution, abnormal naris lateral side alx3 expression increased distribution, abnormal
Kenny et al., 2022	Fig. 2		tfap2ats213/ts213	head melanocyte decreased amount, abnormal head melanocyte low saturation, abnormal trunk melanocyte decreased amount, abnormal trunk melanocyte low saturation, abnormal
	Fig. S6		tfap2ats213/ts213	whole organism tfap2a expression decreased amount, abnormal whole organism tfap2b expression decreased amount, abnormal whole organism tfap2c expression increased amount, abnormal whole organism tfap2d expression decreased amount, abnormal whole organism tfap2e expression decreased amount, abnormal
Bryan et al., 2020	Fig. S1		tfap2ats213/ts213; vu234Tg; z200Tg	closure of optic fissure decreased occurrence, abnormal optic cup anatomical region has fewer parts of type neural crest cell, abnormal optic cup morphogenesis involved in camera-type eye development process quality, abnormal
Chambers et al., 2019	Fig. 1		TU + MO4-tfap2a ,   tfap2am819/+; tfap2ant30/+ ,   tfap2ant30/nt30	embryonic viscerocranium morphogenesis decreased process quality, abnormal heart edematous, abnormal Meckel's cartilage malformed, abnormal pharyngeal arch dlx2a expression decreased amount, abnormal pharyngeal arch malformed, abnormal pronephric distal early tubule kcnj1a.1 expression absent, abnormal pronephric distal early tubule slc12a1 expression decreased amount, abnormal pronephric distal early tubule apical part of cell ab1-slc12a labeling absent, abnormal pronephric distal early tubule early distal convoluted tubule development decreased occurrence, abnormal pronephric distal early tubule nucleus tfap2a expression absent, abnormal whole organism tfap2a expression decreased amount, abnormal
	Fig. 2		tfap2ant30/nt30	hindbrain tfap2b expression decreased amount, abnormal pronephros distal region tfap2b expression decreased amount, abnormal pronephros distal region tfap2b expression decreased distribution, abnormal
	Fig. 3		TU + MO4-tfap2a ,   tfap2ant30/nt30	pronephric distal early tubule clcnk expression decreased amount, abnormal pronephric distal early tubule clcnk expression decreased distribution, abnormal pronephric distal early tubule slc12a1 expression decreased amount, abnormal pronephric distal early tubule slc12a1 expression decreased distribution, abnormal pronephric distal early tubule pronephric nephron tubule epithelial cell differentiation decreased occurrence, abnormal pronephric distal late tubule slc12a3 expression decreased amount, abnormal pronephric distal late tubule slc12a3 expression decreased distribution, abnormal pronephric distal late tubule pronephric nephron tubule epithelial cell differentiation decreased occurrence, abnormal pronephros distal region clcnk expression decreased amount, abnormal pronephros distal region clcnk expression decreased distribution, abnormal
	Fig. 4		tfap2ant30/nt30 ,   tfap2ant30/nt30; x24Tg	pronephric distal early tubule kcnj1a.1 expression amount, ameliorated pronephric distal early tubule kcnj1a.1 expression decreased amount, abnormal pronephric distal early tubule kcnj1a.1 expression decreased distribution, abnormal pronephric distal early tubule kcnj1a.1 expression position, ameliorated pronephric distal early tubule pronephric nephron tubule epithelial cell differentiation decreased occurrence, abnormal pronephric distal early tubule pronephric nephron tubule epithelial cell differentiation occurrence, ameliorated pronephric distal late tubule pronephric nephron tubule epithelial cell differentiation occurrence, abnormal pronephric proximal straight tubule pronephric nephron tubule epithelial cell differentiation occurrence, abnormal
	Fig. 5		tfap2ant30/nt30	notochord apoptotic process increased occurrence, abnormal pharyngeal arch dlx2a expression decreased amount, abnormal pronephric distal early tubule slc12a1 expression decreased amount, abnormal pronephric distal early tubule kidney epithelial cell decreased size, abnormal pronephric distal early tubule nucleus decreased size, abnormal
	Fig. 6		TU + MO4-tfap2a ,   tfap2ant30/nt30	pronephric distal early tubule irx1a expression decreased amount, abnormal pronephric distal early tubule irx1a expression decreased distribution, abnormal pronephric distal early tubule kcnj1a.1 expression absent, abnormal
Dooley et al., 2019	Fig 2		tfap2asa24445/sa24445	caudal fin melanocyte decreased amount, abnormal
	Fig. 3		tfap2asa24445/sa24445	whole organism tfap2a expression decreased amount, abnormal
	Fig. 4		tfap2asa24445/sa24445	whole organism tfap2c expression increased amount, abnormal
Damm et al., 2017	Fig. 5		tfap2ats213/ts213	hematopoietic multipotent progenitor cell myb expression decreased amount, abnormal hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal hematopoietic multipotent progenitor cell decreased amount, abnormal hematopoietic progenitor cell differentiation decreased occurrence, abnormal T cell decreased amount, abnormal thymus rag1 expression decreased amount, abnormal trunk neural crest cell migration arrested, abnormal
Seberg et al., 2017	Fig. 1		tfap2ats213/ts213	melanocyte decreased amount, abnormal pigmentation delayed, abnormal trunk dct expression decreased amount, abnormal trunk mc1r expression decreased amount, abnormal trunk oca2 expression decreased amount, abnormal trunk pmela expression decreased amount, abnormal trunk slc45a2 expression decreased amount, abnormal trunk tyr expression decreased amount, abnormal trunk tyrp1b expression decreased amount, abnormal
	Fig. 5		tfap2ats213/ts213	caudal fin melanocyte decreased amount, abnormal caudal fin ventral region decreased pigmentation, abnormal
Kantarci et al., 2015	Fig. 2		tfap2am819/m819 ,   AB + MO4-tfap2a	otic vesicle has fewer parts of type otic vesicle neuroblast (sensu Vertebrata), abnormal otic vesicle neuroblast fate specification decreased occurrence, abnormal
	Fig. 3		tfap2am819/m819	statoacoustic (VIII) ganglion has extra parts of type statoacoustic (VIII) ganglion neuroblast (sensu Vertebrata), abnormal
	Fig. 4		tfap2am819/m819 ,   AB + MO4-tfap2a	otic vesicle neurogenesis decreased occurrence, abnormal statoacoustic (VIII) ganglion has fewer parts of type statoacoustic (VIII) ganglion neuron, abnormal statoacoustic (VIII) ganglion neuron differentiation decreased rate, abnormal
	Fig. 6		tfap2am819/m819	otic vesicle fibroblast growth factor receptor signaling pathway increased process quality, abnormal otic vesicle Notch signaling pathway increased process quality, abnormal
Wang et al., 2011	Fig. 1		tfap2am610/m610	dorsal root ganglion neuron decreased amount, abnormal enteric nervous system neuron decreased amount, abnormal peripheral nervous system neuron distributed, abnormal pharyngeal arch 2 skeleton decreased size, abnormal pharyngeal arch 2 skeleton morphology, abnormal pharyngeal arch 3-7 skeleton decreased size, abnormal pharyngeal arch 3-7 skeleton morphology, abnormal
Kastenhuber et al., 2010	Fig. 4		WT + MO3-tfap2a	anterior catecholaminergic tract decreased size, abnormal locus coeruleus adrenergic neuron absent, abnormal medulla oblongata adrenergic neuron absent, abnormal
	Fig. 5		tfap2am819/m819 (AB/TL)	locus coeruleus adrenergic neuron absent, abnormal medulla oblongata adrenergic neuron absent, abnormal
Van Otterloo et al., 2010	Fig. 3		tfap2ats213/ts213	melanocyte decreased amount, abnormal
	Fig. 4		tfap2ats213/ts213	pigment cell decreased amount, abnormal
	Fig. 5		tfap2ats213/ts213	melanocyte decreased amount, abnormal melanocyte differentiation disrupted, abnormal
	Fig. 6		WT + MO2-tfap2a	melanocyte decreased amount, abnormal
Arduini et al., 2009	Fig. 1		tfap2ats213/ts213	autonomic nervous system development disrupted, abnormal ceratobranchial cartilage decreased amount, abnormal dorsal root ganglion neuron decreased amount, abnormal enteric nervous system neuron decreased amount, abnormal mandibular arch skeleton disorganized, abnormal mandibular arch skeleton protruding, abnormal peripheral nervous system development disrupted, abnormal pharyngeal arch 2 disorganized, abnormal whole organism lacks all parts of type sympathetic nervous system neuron, abnormal
Gestri et al., 2009	Fig. 4		WT + MO2-tfap2a	ceratohyal cartilage hypoplastic, abnormal ceratohyal cartilage medially rotated, abnormal eye decreased size, abnormal optic fissure closure incomplete, abnormal palatoquadrate cartilage disorganized, abnormal retinal pigmented epithelium mislocalised, abnormal retinal pigmented epithelium protruding, abnormal
Hoffman et al., 2007	Fig. 5		ir937Tg + MO3-tfap2a	mandibular arch skeleton malformed, abnormal
Li et al., 2007	Fig. 2		tfap2ats213/ts213	melanocyte decreased amount, abnormal
	Fig. 3		tfap2ats213/ts213	ceratobranchial cartilage decreased size, abnormal melanocyte decreased amount, abnormal pharyngeal arch 2 skeleton decreased size, abnormal
Phenotype Annotation (1994-2006)	Fig. for (m610)		tfap2am610/m610 (AB)	eye decreased size, abnormal pharyngeal arch 3-7 skeleton quality, abnormal
	Fig. for (m780)		tfap2am780/m780 (AB)	eye decreased size, abnormal pharyngeal arch 3-7 skeleton quality, abnormal
	Fig. for (m819)		tfap2am819/m819	brain quality, abnormal hindbrain quality, abnormal nervous system quality, abnormal pharyngeal arch 3-7 skeleton quality, abnormal
	Fig. for (ts213)		tfap2ats213/ts213	melanocyte irregular spatial pattern, abnormal mouth quality, abnormal pharyngeal arch 3-7 skeleton quality, abnormal whole organism lethal (sensu genetics), abnormal
Neuhauss et al., 1996	Fig. 2		tfap2am610/m610 (AB)	basihyal cartilage decreased length, abnormal basihyal cartilage decreased size, abnormal basihyal cartilage mislocalised laterally, abnormal ceratohyal cartilage decreased size, abnormal hyosymplectic cartilage decreased size, abnormal Meckel's cartilage decreased length, abnormal Meckel's cartilage decreased size, abnormal pharyngeal arch 3-7 skeleton has fewer parts of type ceratobranchial cartilage, abnormal pharyngeal arch cartilage decreased size, abnormal quadrate decreased length, abnormal quadrate decreased size, abnormal trabecula communis absent, abnormal trabecula cranii decreased length, abnormal trabecula cranii decreased thickness, abnormal
	Table 1		tfap2am780/m780 (AB) ,   tfap2am610/m610 (AB)	basihyal cartilage decreased length, abnormal basihyal cartilage decreased size, abnormal basihyal cartilage mislocalised laterally, abnormal ceratohyal cartilage decreased size, abnormal eye decreased size, abnormal hyosymplectic cartilage decreased size, abnormal Meckel's cartilage decreased length, abnormal Meckel's cartilage decreased size, abnormal pharyngeal arch 3-7 skeleton has fewer parts of type ceratobranchial cartilage, abnormal pharyngeal arch cartilage decreased size, abnormal pigmentation disrupted, abnormal quadrate decreased length, abnormal quadrate decreased size, abnormal trabecula communis absent, abnormal trabecula cranii decreased length, abnormal trabecula cranii decreased thickness, abnormal
Schilling et al., 1996	Fig. 2		tfap2ats213/ts213	gill decreased size, abnormal mandibular arch skeleton mislocalised ventrally, abnormal pharyngeal arch 3-7 decreased size, abnormal
	Fig. 3		tfap2ats213/ts213	hyosymplectic cartilage decreased size, abnormal Meckel's cartilage sloped downward, abnormal palatoquadrate cartilage mislocalised, abnormal pharyngeal arch 4 skeleton absent, abnormal pharyngeal arch 5 skeleton absent, abnormal
	Fig. 4		tfap2ats213/ts213	ceratobranchial cartilage decreased size, abnormal ceratohyal cartilage decreased size, abnormal Meckel's cartilage fused with Meckel's cartilage, abnormal pharyngeal arch 5 skeleton absent, abnormal
	Fig. 5		tfap2ats213/ts213	ethmoid cartilage split, abnormal neurocranium decreased size, abnormal
	Fig. Table 3		tfap2ats213/ts213	neurocranium decreased size, abnormal
	Fig. Table 4		tfap2ats213/ts213	mandibular arch skeleton decreased size, abnormal pharyngeal arch 2 skeleton decreased size, abnormal pharyngeal arch 3 skeleton decreased size, abnormal pharyngeal arch 4 skeleton absent, abnormal pharyngeal arch 5 skeleton absent, abnormal pharyngeal arch 6 skeleton absent, abnormal pharyngeal arch 7 skeleton decreased size, abnormal