Morpholino

MO1-fgf22

ID
ZDB-MRPHLNO-130911-1
Name
MO1-fgf22
Previous Names
  • fgf22 exon 2/intron 2 spliceblocking MO1 (1)
Target
Sequence
5' - ATGCGATGTACCTACCGATCCGAAAG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Splice-blocking MO.
Genome Resources
None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO1-fgf22
Expressed Gene Anatomy Figures
ascl1a Fig. 3 from Miyake et al., 2023
bmp5 Fig. 5 with image from Miyake et al., 2013
dlx2a Fig. 2 from Miyake et al., 2023
emx1 Fig. 2 from Miyake et al., 2023
en2a Fig. 4 with image from Miyake et al., 2013
fgf3 Fig. 8 with image from Miyake et al., 2013
fgf8a Fig. 8 with image from Miyake et al., 2013
gad1b Fig. 3 from Miyake et al., 2023
glula Fig. 4 from Miyake et al., 2023
her5 Fig. 4 with image from Miyake et al., 2013
isl1a Fig. 3 from Miyake et al., 2023
lmx1ba Fig. 5 with image from Miyake et al., 2013
meis2a Fig. 6 with image from Miyake et al., 2013
msx1b Fig. 5 with image from Miyake et al., 2013
neurog1 Fig. 3 from Miyake et al., 2023
nkx6.2 Fig. 6 with image from Miyake et al., 2013
olig2 Fig. 4 from Miyake et al., 2023
otx2b Fig. 6 with image from Miyake et al., 2013
pax2a Fig. 4 with image from Miyake et al., 2013
pax6a Fig. 2 from Miyake et al., 2023
pax7a Fig. 6 with image from Miyake et al., 2013
plp1a Fig. 4 from Miyake et al., 2023
shha Fig. 7 with image from Miyake et al., 2013
slc17a6a Fig. 3 from Miyake et al., 2023
wnt1 Fig. 4 with image,  Fig. 5 with image from Miyake et al., 2013
Phenotype
Phenotype resulting from MO1-fgf22
Phenotype Fish Figures
brain glula expression decreased amount, abnormal WT + MO1-fgf22 Fig. 4 from Miyake et al., 2023
cell proliferation in midbrain decreased occurrence, abnormal WT + MO1-fgf22 Fig. 3 with image from Miyake et al., 2013
diencephalon neurog1 expression decreased amount, abnormal WT + MO1-fgf22 Fig. 3 from Miyake et al., 2023
diencephalon isl1a expression decreased amount, abnormal WT + MO1-fgf22 Fig. 3 from Miyake et al., 2023
diencephalon ventral region slc17a6a expression decreased amount, abnormal WT + MO1-fgf22 Fig. 3 from Miyake et al., 2023
dorsal telencephalon anterior region neurog1 expression decreased amount, abnormal WT + MO1-fgf22 Fig. 3 from Miyake et al., 2023
dorsal telencephalon anterior region slc17a6a expression decreased amount, abnormal WT + MO1-fgf22 Fig. 3 from Miyake et al., 2023
epiphysis isl1a expression decreased amount, abnormal WT + MO1-fgf22 Fig. 3 from Miyake et al., 2023
forebrain ascl1a expression decreased amount, abnormal WT + MO1-fgf22 Fig. 3 from Miyake et al., 2023
forebrain olig2 expression increased amount, abnormal WT + MO1-fgf22 Fig. 4 from Miyake et al., 2023
forebrain plp1a expression increased amount, abnormal WT + MO1-fgf22 Fig. 4 from Miyake et al., 2023
forebrain morphology, abnormal WT + MO1-fgf22 + MO4-tp53 Fig. 2 with image from Miyake et al., 2013
forebrain development disrupted, abnormal WT + MO1-fgf22 Fig. 2 with image from Miyake et al., 2013
midbrain plp1a expression mislocalised, abnormal WT + MO1-fgf22 Fig. 4 from Miyake et al., 2023
midbrain morphology, abnormal WT + MO1-fgf22 + MO4-tp53 Fig. 2 with image from Miyake et al., 2013
midbrain development disrupted, abnormal WT + MO1-fgf22 Fig. 2 with image,  Fig. 5 with image from Miyake et al., 2013
midbrain hindbrain boundary morphology, abnormal WT + MO1-fgf22 + MO4-tp53 Fig. 2 with image from Miyake et al., 2013
midbrain-hindbrain boundary development disrupted, abnormal WT + MO1-fgf22 + MO4-tp53 Fig. 2 with image from Miyake et al., 2013
roof plate formation disrupted, abnormal WT + MO1-fgf22 Fig. 4 with image from Miyake et al., 2013
roof plate midbrain region increased width, abnormal WT + MO1-fgf22 Fig. 4 with image from Miyake et al., 2013
telencephalon isl1a expression decreased amount, abnormal WT + MO1-fgf22 Fig. 3 from Miyake et al., 2023
telencephalon gad1b expression decreased amount, abnormal WT + MO1-fgf22 Fig. 3 from Miyake et al., 2023
ventral telencephalon dlx2a expression decreased amount, abnormal WT + MO1-fgf22 Fig. 2 from Miyake et al., 2023
ventral telencephalon gad1b expression decreased amount, abnormal WT + MO1-fgf22 Fig. 3 from Miyake et al., 2023
ventral thalamus dlx2a expression decreased amount, abnormal WT + MO1-fgf22 Fig. 2 from Miyake et al., 2023
Phenotype of all Fish created by or utilizing MO1-fgf22
Phenotype Fish Conditions Figures
forebrain olig2 expression increased amount, abnormal WT + MO1-fgf22 standard conditions Fig. 4 from Miyake et al., 2023
diencephalon ventral region slc17a6a expression decreased amount, abnormal WT + MO1-fgf22 standard conditions Fig. 3 from Miyake et al., 2023
roof plate midbrain region increased width, abnormal WT + MO1-fgf22 standard conditions Fig. 4 with image from Miyake et al., 2013
midbrain plp1a expression mislocalised, abnormal WT + MO1-fgf22 standard conditions Fig. 4 from Miyake et al., 2023
ventral thalamus dlx2a expression decreased amount, abnormal WT + MO1-fgf22 standard conditions Fig. 2 from Miyake et al., 2023
ventral telencephalon gad1b expression decreased amount, abnormal WT + MO1-fgf22 standard conditions Fig. 3 from Miyake et al., 2023
dorsal telencephalon anterior region neurog1 expression decreased amount, abnormal WT + MO1-fgf22 standard conditions Fig. 3 from Miyake et al., 2023
roof plate formation disrupted, abnormal WT + MO1-fgf22 standard conditions Fig. 4 with image from Miyake et al., 2013
cell proliferation in midbrain decreased occurrence, abnormal WT + MO1-fgf22 standard conditions Fig. 3 with image from Miyake et al., 2013
midbrain hindbrain boundary morphology, abnormal WT + MO1-fgf22 standard conditions Fig. 2 with image from Miyake et al., 2013
ventral telencephalon dlx2a expression decreased amount, abnormal WT + MO1-fgf22 standard conditions Fig. 2 from Miyake et al., 2023
telencephalon isl1a expression decreased amount, abnormal WT + MO1-fgf22 standard conditions Fig. 3 from Miyake et al., 2023
forebrain ascl1a expression decreased amount, abnormal WT + MO1-fgf22 standard conditions Fig. 3 from Miyake et al., 2023
forebrain development disrupted, abnormal WT + MO1-fgf22 standard conditions Fig. 2 with image from Miyake et al., 2013
telencephalon gad1b expression decreased amount, abnormal WT + MO1-fgf22 standard conditions Fig. 3 from Miyake et al., 2023
midbrain-hindbrain boundary development disrupted, abnormal WT + MO1-fgf22 standard conditions Fig. 2 with image from Miyake et al., 2013
diencephalon isl1a expression decreased amount, abnormal WT + MO1-fgf22 standard conditions Fig. 3 from Miyake et al., 2023
epiphysis isl1a expression decreased amount, abnormal WT + MO1-fgf22 standard conditions Fig. 3 from Miyake et al., 2023
midbrain development disrupted, abnormal WT + MO1-fgf22 standard conditions Fig. 2 with image,  Fig. 5 with image from Miyake et al., 2013
diencephalon neurog1 expression decreased amount, abnormal WT + MO1-fgf22 standard conditions Fig. 3 from Miyake et al., 2023
midbrain morphology, abnormal WT + MO1-fgf22 standard conditions Fig. 2 with image from Miyake et al., 2013
forebrain plp1a expression increased amount, abnormal WT + MO1-fgf22 standard conditions Fig. 4 from Miyake et al., 2023
forebrain morphology, abnormal WT + MO1-fgf22 standard conditions Fig. 2 with image from Miyake et al., 2013
dorsal telencephalon anterior region slc17a6a expression decreased amount, abnormal WT + MO1-fgf22 standard conditions Fig. 3 from Miyake et al., 2023
brain glula expression decreased amount, abnormal WT + MO1-fgf22 standard conditions Fig. 4 from Miyake et al., 2023
forebrain development disrupted, abnormal WT + MO1-fgf22 + MO4-tp53 standard conditions Fig. 2 with image from Miyake et al., 2013
midbrain-hindbrain boundary development disrupted, abnormal WT + MO1-fgf22 + MO4-tp53 standard conditions Fig. 2 with image from Miyake et al., 2013
midbrain development disrupted, abnormal WT + MO1-fgf22 + MO4-tp53 standard conditions Fig. 2 with image from Miyake et al., 2013
midbrain hindbrain boundary morphology, abnormal WT + MO1-fgf22 + MO4-tp53 standard conditions Fig. 2 with image from Miyake et al., 2013
forebrain morphology, abnormal WT + MO1-fgf22 + MO4-tp53 standard conditions Fig. 2 with image from Miyake et al., 2013
midbrain morphology, abnormal WT + MO1-fgf22 + MO4-tp53 standard conditions Fig. 2 with image from Miyake et al., 2013
Citations
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