Morpholino

MO2-wnt8a

ID
ZDB-MRPHLNO-041217-13
Name
MO2-wnt8a
Previous Names
  • wnt8-2MO (1)
  • wnt8-MO2 (1)
  • wnt8-orf2 (1)
  • wnt8MO2 (1)
Target
Sequence
5' - GCCCAACGGAAGAAGTAAGCCATTA - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO2-wnt8a
Expressed Gene Anatomy Figures
chrd Fig. 1 from Lu et al., 2014
Fig. 5 with image from Xiong et al., 2006
otx2b Fig. 5 with image from Xiong et al., 2006
tbx16l Fig. 5 with image from Xiong et al., 2006
Phenotype
Phenotype resulting from MO2-wnt8a
Phenotype Fish Figures
axial mesoderm chrd expression increased amount, abnormal AB/TU + MO2-wnt8a Fig. 1 from Lu et al., 2014
axial mesoderm chrd expression increased distribution, abnormal AB/TU + MO2-wnt8a Fig. 1 from Lu et al., 2014
brain poorly differentiated, abnormal WT + MO2-wnt8a Fig. 7 from Lekven et al., 2001
canonical Wnt signaling pathway decreased occurrence, abnormal AB/TU + MO2-wnt8a Fig. 2 from Lu et al., 2014
caudal fin posterior region absent, abnormal AB/TU + MO2-wnt8a Fig. 1 from Lu et al., 2014
caudal fin ventral region absent, abnormal AB/TU + MO2-wnt8a Fig. 1 from Lu et al., 2014
ectodermal cell nucleus ab1-ctnnb labeling absent, abnormal AB/TU + MO2-wnt8a Fig. 3 from Lu et al., 2014
forebrain apoptotic, abnormal WT + MO2-wnt8a Fig. 7 from Lekven et al., 2001
notochord undulate, abnormal WT + MO2-wnt8a Fig. 7 from Lekven et al., 2001
presumptive mesoderm nucleus ab1-ctnnb labeling absent, abnormal AB/TU + MO2-wnt8a Fig. 3 from Lu et al., 2014
trunk posterior region absent, abnormal AB/TU + MO2-wnt8a Fig. 1 from Lu et al., 2014
trunk ventral region absent, abnormal AB/TU + MO2-wnt8a Fig. 1 from Lu et al., 2014
ventral mesoderm chrd expression mislocalised, abnormal AB/TU + MO2-wnt8a Fig. 1 from Lu et al., 2014
Phenotype of all Fish created by or utilizing MO2-wnt8a
Phenotype Fish Conditions Figures
whole organism decreased length, abnormal AB + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
tail bud decreased length, abnormal AB + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
tail bud morphology, abnormal AB + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Thorpe et al., 2005
post-vent region decreased length, abnormal AB + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
post-anal tail morphogenesis disrupted, abnormal AB + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
caudal fin posterior region absent, abnormal AB/TU + MO2-wnt8a standard conditions Fig. 1 from Lu et al., 2014
canonical Wnt signaling pathway decreased occurrence, abnormal AB/TU + MO2-wnt8a control Fig. 2 from Lu et al., 2014
caudal fin ventral region absent, abnormal AB/TU + MO2-wnt8a standard conditions Fig. 1 from Lu et al., 2014
axial mesoderm chrd expression increased amount, abnormal AB/TU + MO2-wnt8a standard conditions Fig. 1 from Lu et al., 2014
ectodermal cell nucleus ab1-ctnnb labeling absent, abnormal AB/TU + MO2-wnt8a standard conditions Fig. 3 from Lu et al., 2014
presumptive mesoderm nucleus ab1-ctnnb labeling absent, abnormal AB/TU + MO2-wnt8a standard conditions Fig. 3 from Lu et al., 2014
trunk posterior region absent, abnormal AB/TU + MO2-wnt8a standard conditions Fig. 1 from Lu et al., 2014
trunk ventral region absent, abnormal AB/TU + MO2-wnt8a standard conditions Fig. 1 from Lu et al., 2014
axial mesoderm chrd expression increased distribution, abnormal AB/TU + MO2-wnt8a standard conditions Fig. 1 from Lu et al., 2014
ventral mesoderm chrd expression mislocalised, abnormal AB/TU + MO2-wnt8a standard conditions Fig. 1 from Lu et al., 2014
telencephalon increased size, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Li et al., 2011
Fig. 3 from Ding et al., 2008
Fig. 3 from Gan et al., 2008
pronephric tubule cell increased distance pronephric tubule cell, abnormal TU + MO1-wnt8a + MO2-wnt8a chemical treatment by environment: aphidicolin, chemical treatment by environment: hydroxyurea Fig. 7 with image from Naylor et al., 2017
tail bud protruding, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 from Ding et al., 2008
pronephric tubule distal region slc12a3 expression decreased distribution, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 7 with image from Naylor et al., 2017
common myeloid progenitor spi1b expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 8 with image from Naylor et al., 2017
pronephric tubule cell increased distance pronephric tubule cell, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 7 with image from Naylor et al., 2017
pronephric tubule distal region slc12a3 expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 7 with image from Naylor et al., 2017
pronephric tubule proximal region has number of cell, ameliorated TU + MO1-wnt8a + MO2-wnt8a chemical treatment by environment: 6-bromoindirubin-3'-oxime Fig. 3 with image from Naylor et al., 2017
post-vent region decreased length, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Li et al., 2011
pronephric tubule cell population proliferation decreased occurrence, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 6 with image from Naylor et al., 2017
whole organism decreased size, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 2 with image from Naylor et al., 2017
whole organism wholly dorsalized, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 from Ding et al., 2008
presumptive ventral mesoderm cdx4 expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
whole organism shape, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 from Ding et al., 2008
shield increased width, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Li et al., 2011
erythroid lineage cell gata1a expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 8 with image from Naylor et al., 2017
pronephric tubule proximal region has fewer parts of type cell, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 3 with image from Naylor et al., 2017
post-vent region decreased size, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 from Ding et al., 2008
Fig. 3 from Gan et al., 2008
pronephros pax2a expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 3 with image from Naylor et al., 2017
pronephric tubule Ab1-hnf1b labeling decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 3 with image from Naylor et al., 2017
canonical Wnt signaling pathway decreased process quality, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
trunk decreased length, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Li et al., 2011
whole organism wholly anteriorized, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 from Gan et al., 2008
pronephric tubule Ab1-hnf1b labeling amount, ameliorated TU + MO1-wnt8a + MO2-wnt8a chemical treatment by environment: 6-bromoindirubin-3'-oxime Fig. 3 with image from Naylor et al., 2017
caudal fin morphology, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 2 with image from Naylor et al., 2017
head increased size, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 from Gan et al., 2008
trunk posterior region absent, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 2 with image from Naylor et al., 2017
pronephros pax2a expression amount, ameliorated TU + MO1-wnt8a + MO2-wnt8a chemical treatment by environment: 6-bromoindirubin-3'-oxime Fig. 3 with image from Naylor et al., 2017
caudal fin absent, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 2 with image from Naylor et al., 2017
presumptive ventral mesoderm tbx6 expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
pronephric tubule slc12a3 expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Naylor et al., 2017
histone H4K20 methyltransferase activity disrupted, abnormal TU + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Li et al., 2011
apoptotic process decreased occurrence, abnormal TU + MO1-wnt8a + MO2-wnt8a + MO4-tp53 standard conditions Fig. 4 with image from Naylor et al., 2017
pronephric tubule slc12a3 expression decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a + MO4-tp53 standard conditions Fig. 4 with image from Naylor et al., 2017
whole organism posterior region ab1-casp3 labeling decreased amount, abnormal TU + MO1-wnt8a + MO2-wnt8a + MO4-tp53 standard conditions Fig. 4 with image from Naylor et al., 2017
midbrain decreased size, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 7 from Lekven et al., 2001
presumptive mesoderm wholly dorsalized, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 6 from Lekven et al., 2001
forebrain increased size, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. S1 from Kagermeier-Schenk et al., 2011
forebrain prominent, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 7 from Lekven et al., 2001
whole organism wholly dorsalized, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 6 with image from Wylie et al., 2014
somite decreased amount, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 7 from Lekven et al., 2001
post-vent region decreased size, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 7 from Lekven et al., 2001
post-vent region decreased length, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. Table 1 from Shimizu et al., 2005
Fig. 7 from Lekven et al., 2001
whole organism dorsal region gsc expression increased distribution, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Kagermeier-Schenk et al., 2011
head increased size, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. Table 1 from Shimizu et al., 2005
telencephalon increased size, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Waxman et al., 2004
eye increased size, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. S1 from Kagermeier-Schenk et al., 2011
embryonic pattern specification disrupted, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 6 from Lekven et al., 2001
presumptive neural plate wholly anteriorized, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 6 from Lekven et al., 2001
post-vent region kinked, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. Table 1 from Shimizu et al., 2005
post-vent region has fewer parts of type somite, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. Table 1 from Shimizu et al., 2005
trunk decreased size, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 7 from Lekven et al., 2001
forebrain distended, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 7 from Lekven et al., 2001
whole organism posterior region absent, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. S1 from Kagermeier-Schenk et al., 2011
presumptive telencephalon foxg1a expression increased distribution, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Kagermeier-Schenk et al., 2011
margin tpbg1b expression decreased distribution, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. S1 from Kagermeier-Schenk et al., 2011
post-vent region curved ventral, abnormal WT + MO1-wnt8a + MO2-wnt8a standard conditions Fig. Table 1 from Shimizu et al., 2005
whole organism dead, abnormal WT + MO1-wnt8a + MO2-wnt8a + MO7-wnt8a standard conditions Fig. 6 with image from Wylie et al., 2014
whole organism wholly dorsalized, abnormal WT + MO1-wnt8a + MO2-wnt8a + MO7-wnt8a standard conditions Fig. 6 with image from Wylie et al., 2014
forebrain apoptotic, abnormal WT + MO2-wnt8a standard conditions Fig. 7 from Lekven et al., 2001
notochord undulate, abnormal WT + MO2-wnt8a standard conditions Fig. 7 from Lekven et al., 2001
brain poorly differentiated, abnormal WT + MO2-wnt8a standard conditions Fig. 7 from Lekven et al., 2001
canonical Wnt signaling pathway decreased process quality, abnormal cdkn2aipcas009/cas009 + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm tbx6 expression decreased amount, abnormal cdkn2aipcas009/cas009 + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm cdx4 expression decreased amount, abnormal cdkn2aipcas009/cas009 + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
canonical Wnt signaling pathway decreased process quality, abnormal cdkn2aipcas009/cas009 + MO1-wnt8a + MO2-wnt8a + MO7-tp53 control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm tbx6 expression decreased amount, abnormal cdkn2aipcas009/cas009 + MO1-wnt8a + MO2-wnt8a + MO7-tp53 control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm cdx4 expression decreased amount, abnormal cdkn2aipcas009/cas009 + MO1-wnt8a + MO2-wnt8a + MO7-tp53 control Fig. 4 with image from He et al., 2017
post-vent region aplastic, abnormal tbx16b104/b104 + MO1-wnt8a + MO2-wnt8a (AB) standard conditions Fig. 7 from Lekven et al., 2001
somite aplastic, abnormal tbx16b104/b104 + MO1-wnt8a + MO2-wnt8a (AB) standard conditions Fig. 7 from Lekven et al., 2001
trunk aplastic, abnormal tbx16b104/b104 + MO1-wnt8a + MO2-wnt8a (AB) standard conditions Fig. 7 from Lekven et al., 2001
trunk aplastic, abnormal tbxtab160/b160 + MO1-wnt8a + MO2-wnt8a (AB) standard conditions Fig. 7 from Lekven et al., 2001
somite structure, abnormal tbxtab160/b160 + MO1-wnt8a + MO2-wnt8a (AB) standard conditions Fig. 7 from Lekven et al., 2001
somite decreased amount, abnormal tbxtab160/b160 + MO1-wnt8a + MO2-wnt8a (AB) standard conditions Fig. 7 from Lekven et al., 2001
somite fused with somite, abnormal tbxtab160/b160 + MO1-wnt8a + MO2-wnt8a (AB) standard conditions Fig. 7 from Lekven et al., 2001
post-vent region aplastic, abnormal tbxtab160/b160 + MO1-wnt8a + MO2-wnt8a (AB) standard conditions Fig. 7 from Lekven et al., 2001
tail bud decreased length, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
somite decreased amount, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Thorpe et al., 2005
post-anal tail morphogenesis disrupted, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
notochord truncated, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Thorpe et al., 2005
central canal dilated, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Thorpe et al., 2005
tail bud bent, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Thorpe et al., 2005
post-vent region decreased length, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
whole organism decreased length, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 1 with image from Thorpe et al., 2005
tail bud morphology, abnormal AB + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Thorpe et al., 2005
canonical Wnt signaling pathway decreased process quality, abnormal TU + MO1-cdkn2aip + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm tbx6 expression decreased amount, abnormal TU + MO1-cdkn2aip + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm cdx4 expression decreased amount, abnormal TU + MO1-cdkn2aip + MO1-wnt8a + MO2-wnt8a control Fig. 4 with image from He et al., 2017
canonical Wnt signaling pathway decreased process quality, abnormal TU + MO1-cdkn2aip + MO1-wnt8a + MO2-wnt8a + MO7-tp53 control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm tbx6 expression decreased amount, abnormal TU + MO1-cdkn2aip + MO1-wnt8a + MO2-wnt8a + MO7-tp53 control Fig. 4 with image from He et al., 2017
presumptive ventral mesoderm cdx4 expression decreased amount, abnormal TU + MO1-cdkn2aip + MO1-wnt8a + MO2-wnt8a + MO7-tp53 control Fig. 4 with image from He et al., 2017
post-vent region decreased length, abnormal TU + MO1-kmt5aa + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Li et al., 2011
telencephalon increased size, abnormal TU + MO1-kmt5aa + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Li et al., 2011
trunk decreased length, abnormal TU + MO1-kmt5aa + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 3 with image from Li et al., 2011
telencephalon increased size, abnormal WT + MO1-dact1 + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Waxman et al., 2004
head decreased size, abnormal WT + MO1-dact1 + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Waxman et al., 2004
post-vent region decreased size, abnormal WT + MO1-dact1 + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Waxman et al., 2004
whole organism wholly anteriorized, abnormal WT + MO1-dact1 + MO1-wnt8a + MO2-wnt8a standard conditions Fig. 4 with image from Waxman et al., 2004
whole organism frzb expression amount, ameliorated WT + MO1-nanog + MO1-wnt8a + MO2-wnt8a standard conditions Fig 3 with image from He et al., 2020
whole organism emx1 expression amount, ameliorated WT + MO1-nanog + MO1-wnt8a + MO2-wnt8a standard conditions Fig 3 with image from He et al., 2020
whole organism dkk1b expression amount, ameliorated WT + MO1-nanog + MO1-wnt8a + MO2-wnt8a standard conditions Fig 3 with image from He et al., 2020
whole organism six3b expression increased amount, abnormal WT + MO1-nanog + MO1-wnt8a + MO2-wnt8a standard conditions Fig 3 with image from He et al., 2020
whole organism sp5l expression position, ameliorated WT + MO1-nanog + MO1-wnt8a + MO2-wnt8a standard conditions Fig 3 with image from He et al., 2020
post-vent region has fewer parts of type somite, abnormal WT + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. Table 1 from Shimizu et al., 2005
post-vent region truncated, abnormal WT + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. Table 1 from Shimizu et al., 2005
head increased size, abnormal WT + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. Table 1 from Shimizu et al., 2005
post-vent region decreased length, abnormal WT + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. Table 1 from Shimizu et al., 2005
post-vent region kinked, abnormal WT + MO1-wnt3a + MO1-wnt8a + MO2-wnt8a standard conditions Fig. Table 1 from Shimizu et al., 2005
post-vent region decreased length, abnormal WT + MO1-wnt8a + MO2-wnt3a + MO2-wnt8a standard conditions Fig. Table 1 from Shimizu et al., 2005
head increased size, abnormal WT + MO1-wnt8a + MO2-wnt3a + MO2-wnt8a standard conditions Fig. Table 1 from Shimizu et al., 2005
post-vent region has fewer parts of type somite, abnormal WT + MO1-wnt8a + MO2-wnt3a + MO2-wnt8a standard conditions Fig. Table 1 from Shimizu et al., 2005
post-vent region kinked, abnormal WT + MO1-wnt8a + MO2-wnt3a + MO2-wnt8a standard conditions Fig. Table 1 from Shimizu et al., 2005
post-vent region truncated, abnormal WT + MO1-wnt8a + MO2-wnt3a + MO2-wnt8a standard conditions Fig. Table 1 from Shimizu et al., 2005
Citations
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