FIGURE

Fig. 8

ID

ZDB-FIG-241219-36

Publication

Zadmajid et al., 2024 - Testosterone acts through membrane protein GPRC6A to cause cardiac edema in zebrafish embryos

Other Figures

All Figure Page

Back to All Figure Page

Fig. 8

Testosterone directly acts on GPRC6A in zebrafish embryos. (A) Wild-type embryos at 3 h post-fertilization were exposed to vehicle, estradiol or testosterone. Cardiac edema was assayed at 3 days post fertilization. (B-E) Zebrafish with mutations in aromatase or nuclear estrogen receptors were exposed to testosterone and assayed for morphological phenotypes. Each data point is the mean percentage of embryos in a single clutch exhibiting cardiac edema (20-80 embryos per clutch). Clutches in the same treatment group were assayed on different days. Horizontal lines are the mean of each group. ns, not significant (P>0.05); one-way ANOVA with Tukey's multiple comparisons test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development