FIGURE

Fig. 2

ID

ZDB-FIG-240517-19

Publication

Karas et al., 2024 - Removal of pomt1 in zebrafish leads to loss of α-dystroglycan glycosylation and dystroglycanopathy phenotypes

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Fig. 2

pomt1 KOHet fish show reduced survival and size. (A) Survival is indicated as deviation from expected Mendelian ratios (25% for WTs and KOHets, 50% for Hets) in 3 independent clutches showing a drop in pomt1 KOHet juveniles after 30 dpf. (B) Significant size differences are evident in KOHet fish at 30 dpf, but not in the surviving KOHet fish at 40 dpf. (C) pomt1 KOHet fish at 30 dpf appear underdeveloped with less prominent dorsal and anal fins (asterisks). Scale bar: 2 mm. ***p < 0.001. Alt-text. This figure shows that pomt1 knock-out fish lead to reduced survival and smaller size by 30 dpf.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Hum. Mol. Genet.