FIGURE
Fig. 7
- ID
- ZDB-FIG-230607-16
- Publication
- Rayrikar et al., 2022 - Ccn2a-FGFR1-SHH signaling is necessary for intervertebral disc homeostasis and regeneration in adult zebrafish
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Fig. 7
Ccn2a interacts with Fgfr1a and Fgfr1b in vivo. (A) Schematic of experimental procedures. (B,C) Representative single plane optical sections of whole-mount 30 hpf embryos stained for proximity detection (cyan, interacting complex) and nuclei (white). Arrowheads in B indicate an interaction between C-terminal Myc-tagged Ccn2a and N-terminal FLAG-tagged Fgfr1a (cyan). Arrows in C indicate an interaction between N-terminal Myc-tagged Ccn2a and N-terminal FLAG-tagged Fgfr1b (cyan). (D) Model of the signaling cascade regulated by Ccn2a, which promotes cell proliferation and inhibits cell death. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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