FIGURE

Fig. 4

ID

ZDB-FIG-230315-111

Publication

Zhang et al., 2022 - Deficiency of nde1 in zebrafish induces brain inflammatory responses and autism-like behavior

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Fig. 4

Social behavior analysis of nde1^−/− zebrafish

(A) Schematic of shoaling test.

(B) Significantly increased inter-fish distance of 2 mpf (n = 10) and 3 mpf (n = 10) nde1^−/− zebrafish.

(D) Time ratio and distance ratio in the social area were significantly reduced in 2 mpf (n = 35) and 3 mpf (n = 28) nde1^−/− zebrafish compared with nde1^+/+ zebrafish.

(E) Schematic and representative heatmap of kin recognition and preference test; area1: kin preference area, area2: nonkin preference area.

(F) Significantly increased ratio of kin preference area entering and decreased ratio of nonkin preference area entering in 3 mpf nde1^−/− zebrafish (n = 28).

Data are presented as mean ± SEM; ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	nde1^{zf3784/zf3784} (TU)
Observed In:	social behavior
Stage Range:	Days 45-89 to Adult

Phenotype Detail

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