FIGURE

Fig. 3

ID

ZDB-FIG-230315-110

Publication

Zhang et al., 2022 - Deficiency of nde1 in zebrafish induces brain inflammatory responses and autism-like behavior

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Fig. 3

Zebrafish locomotor activity at 5 dpf, 2 mpf, and 3 mpf

(A) Experimental setup of analysis of 5 dpf locomotor activity.

(B) nde1^+/+ and nde1^−/− larvae (5 dpf) movement trend line graph within 75 min of the experiment time (n = 36).

(D) Activity frequency of ASP at three intensity scales.

(E and G) 2 mpf (E, n = 32) and 3 mpf (G, n = 28) nde1^+/+ and nde1^−/− zebrafish movement trend graph within 30 min of the experiment time.

(F) Comparison of 20 min ASP of locomotor activity of two mpf nde1^+/+ and nde1^−/− zebrafish.

(H) Representative trace of back and forth, big circling and small circling of nde1^−/− zebrafish.

(I and J) 2 mpf (I) and three mpf (J) nde1^−/− zebrafish showed more repetitive behaviors than nde1^+/+.

Data are shown as mean ± SEM; ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	nde1^{zf3784/zf3784} (TU)
Condition:	lighting conditions
Observed In:	swimming behavior
Stage Range:	Day 5 to Adult

Phenotype Detail

Acknowledgments

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