FIGURE

Fig. 1

ID

ZDB-FIG-230115-58

Publication

Brandt et al., 2021 - Ablation of mpeg+ Macrophages Exacerbates mfrp-Related Hyperopia

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Fig. 1

Ablation of macrophages in WT zebrafish did not significantly impact emmetropization. (A) Representative SD-OCT B-scans from the center of mpeg1:NTR-eYFP⁺ eyes and their WT cousins with or without MTZ treatment. (B) Axial length, lens diameter, retinal radius, and body length of mpeg1:NTR-eYFP⁺ fish and their WT cousins with or without MTZ treatment. (C) Axial length normalized to body length and lens diameter. (D) Relative refractive error. Two-way ANOVA was used for statistical analysis for (B) to (D). P values are shown from Tukey's multiple comparisons for post hoc analysis. Red bars indicate statistical significance likely due to mpeg1⁺ cell ablation. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001, ^****P < 0.0001. For mpeg1:NTR-eYFP⁺ untreated, n = 11; for mpeg1:NTR-eYFP⁺ MTZ treated, n = 7; for WT cousins untreated, n = 13; for WT cousins MTZ treated, n = 9.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT w202Tg/w202Tg
Condition:	chemical treatment by environment: metronidazole
Observed In:	lens radial plane retina radial plane whole organism
Stage:	Days 45-89

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Invest. Ophthalmol. Vis. Sci.