FIGURE

FIGURE 3

ID

ZDB-FIG-220406-3

Publication

Zheng et al., 2022 - Kif15 Is Required in the Development of Auditory System Using Zebrafish as a Model

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FIGURE 3

Kif15 inhibition results in decreased hair cells (HCs) in the inner ear. (A–C) The gross morphology of otic vesicle in different groups at 48 hpf using the white light field microscope. u, utricle; s, saccule. Scale bar is 20 μm. (D–F) Representative images of utricular HCs in different groups at 48 hpf. (G–I) Representative images of saccular HCs in different groups at 48 hpf. White star labels the HC. (J) Quantification of the number of HCs in utricle and saccule in control-MO (Con-MO) group (n = 22), Kif15-deficient morphants (n = 22), and Kif15-MO + Kif15 mRNA group. Data are recorded as mean ± SEM. **p < 0.01, ***p < 0.001 vs. Con-MO group; ^##p < 0.01 vs. Kif15-MO group; NS, no significance.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	s356tTg + MO2-kif15
Knockdown Reagent:	MO2-kif15
Observed In:	inner ear hair cell saccule hair cell utricle hair cell
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.