FIGURE
Fig. 4
- ID
- ZDB-FIG-220202-8
- Publication
- Manchanda et al., 2021 - Truncation of the otoferlin transmembrane domain alters the development of hair cells and reduces membrane docking
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Fig. 4
The otofB mutation results in reduced Vglut3 in neuromasts. (A–C) Representative confocal images of 72 hpf (A), 96 hpf (B), and 120 hpf (C) WT neuromasts stained for Vglut3. (D–F) Representative confocal images of 72 hpf (D), 96 hpf (E), and 120 hpf (F) mutant neuromasts stained for Vglut3. (G) Quantification of Vglut3 in WT and OtofB neuromasts (t test, p < 0.001). N = 4 larvae, four neuromasts per larvae for both WT and mutant. (H) Quantification of Vglut3 mRNA transcripts in WT and OtofB larvae (t test, p < 0.001). N = 4 for both WT and mutant. Scale bars = 5 µm. |
Expression Data
| Gene: | |
|---|---|
| Antibody: | |
| Fish: | |
| Anatomical Terms: | |
| Stage Range: | Protruding-mouth to Day 5 |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage Range: | Protruding-mouth to Day 5 |
Phenotype Detail
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