FIGURE

Fig. 2

ID

ZDB-FIG-201117-9

Publication

Xia et al., 2020 - Slc39a5-mediated zinc homeostasis plays an essential role in venous angiogenesis in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

slc39a5 morphants have delayed CVP development. (a–g) Representative images of the caudal region in control and slc39a5 morphant embryos captured using dual-fluorescence microscopy at 32 hpf (a), 38 hpf (d) and 42 hpf (g). The numbers of endothelial sprouts and capillary loops in the CVP were measured at 32 hpf (b–c), 38 hpf (e–f) and 42 hpf (h–i). (j–l) Representative images of the CVP in control Tg(fli1a:eGFP) embryos and Tg(fli1a:eGFP) embryos injected with the slc39a5 morpholino alone or co-injected with the slc39a5 morpholino and a morpholino-resistant slc39a5 mRNA. The numbers of endothelial sprouts (k) and capillary loops (l) in the CVP were measured at 32 hpf. *p < 0.05, ***p < 0.001 and n.s., not significant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cz3325Tg; is5Tg + MO1-slc39a5
Knockdown Reagent:	MO1-slc39a5
Observed In:	blood vessel endothelial cell filopodium caudal vein plexus capillary sprouting angiogenesis
Stage Range:	Prim-15 to High-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Open Biol.