FIGURE

Fig. 8

ID

ZDB-FIG-200306-123

Publication

Nimura et al., 2019 - Role of Reelin in cell positioning in the cerebellum and the cerebellum-like structure in zebrafish

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Fig. 8

Localization of Reln protein in the tectum and the cerebellum. Medial and lateral sagittal sections of the brain from 30-dpf (A–P) and 90-dpf (Q–T) WT and relnΔ7/Δ7 mutant zebrafish were stained with anti-Reln (magenta), anti-Vglut1 (green), and Hoechst (cyan). Three fish for 30-dpf and one fish for 90-dpf WT or relnΔ7/Δ7 mutant fish were analyzed. Typical images are shown. (E-H, M-P) High magnification images of the boxes in C, D, K, and L. In WT, Reln protein was detected strongly in the SM and relatively weakly in the SO in the TeO. Reln was also detected strongly in the ML in the Cb. Weak Reln signals were also detected in the GCs in the TL and the GCL. These signals were absent in relnΔ7/Δ7mutants. CC, crista cerebellaris. The other abbreviations are described in the legend for Fig. 1. Scale bars: 100 μm in A (applies to A-D, I-L); 50 μm in E (applies to E-H, M-P); 200 μm in Q (applies to Q-T).

Expression Data

Genes:	reln slc17a7a
Antibodies:	Ab1-reln Ab1-slc17a7
Fish:	AB reln^nub23/nub23 (AB)
Anatomical Terms:	cerebellar crest cerebellar granule cell molecular layer corpus cerebelli stratum marginale stratum opticum torus longitudinalis torus longitudinalis granule cell
Stage Range:	Days 30-44 to Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	reln^nub23/nub23 (AB)
Observed In:	cerebellar crest cerebellar granule cell molecular layer corpus cerebelli stratum marginale stratum opticum torus longitudinalis granule cell
Stage Range:	Days 30-44 to Adult

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 455(2), Nimura, T., Itoh, T., Hagio, H., Hayashi, T., Di Donato, V., Takeuchi, M., Itoh, T., Inoguchi, F., Sato, Y., Yamamoto, N., Katsuyama, Y., Del Bene, F., Shimizu, T., Hibi, M., Role of Reelin in cell positioning in the cerebellum and the cerebellum-like structure in zebrafish, 393-408, Copyright (2019) with permission from Elsevier. Full text @ Dev. Biol.