FIGURE

Fig. S2

ID

ZDB-FIG-190613-10

Publication

Bise et al., 2019 - Ciliary neurotrophic factor stimulates cardioprotection and the proliferative activity in the adult zebrafish heart

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Fig. S2

Components of the LIFR/GP130 pathway are transcriptionally upregulated after preconditioning. (a) Heat map representation of 20 differentially expressed genes at 1 dpt that contribute to the LIFR/gp130 pathway. Fold changes are represented in log2 scale of fold change (blue: log2 < 0; red: log2 > 0). (b) In-situ hybridization of ventricular sections demonstrates upregulation of several components of the LIFR/GP130 pathway at 1 dpt. n ≥ 3 hearts. (c) Detection of putative LIFR/gp130 ligands at 1 dpt by qRT-PCR. The normalized gene expression was calculated relative to β-actin. n ≥ 3 samples prepared of 10 ventricles. **P < 0.01 with student’s t-test. (d) In-situ hybridization of ventricular sections demonstrates upregulation of cntf transcription at the periphery of the ventricle, at 1 dpt. n ≥ 3 hearts.

Expression Data

Genes:	cntf mmp13a socs3b
Fish:	AB
Condition:	laceration: pericardial region
Anatomical Terms:	cardiac ventricle epicardium
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Condition:	laceration: pericardial region
Observed In:	cardiac ventricle epicardium
Stage:	Adult

Phenotype Detail

Acknowledgments

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