FIGURE

Fig. 5

ID

ZDB-FIG-180711-29

Publication

Selland et al., 2018 - Coordinate regulation of retinoic acid synthesis by pbx genes and fibroblast growth factor signaling by hoxb1b is required for hindbrain patterning and development

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Fig. 5

Vhnf1 requires PG1 hox genes.

Vhnf1 shows reduced expression when both hoxb1b and hoxb1a are lost (5/5 embryos)(D) compared to wildtype (A). This reduction is not observed when either hoxb1a (B) of hoxb1b (C) are lost alone. All embryos have been genotyped for hoxb1a^sa1191 and hoxb1b^ua1006. All images are dorsal views, anterior to the left, 4 somites.

Expression Data

Gene:	hnf1ba
Fish:	AB hoxb1a^{sa1191/sa1191} hoxb1b^{ua1006/ua1006} hoxb1a^{sa1191/sa1191}; hoxb1b^{ua1006/ua1006}
Anatomical Term:	hindbrain neural plate
Stage:	1-4 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hoxb1a^{sa1191/sa1191}; hoxb1b^{ua1006/ua1006}
Observed In:	hindbrain neural plate
Stage:	1-4 somites

Phenotype Detail

Acknowledgments

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Reprinted from Mechanisms of Development, 150, Selland, L.G., Koch, S., Laraque, M., Waskiewicz, A.J., Coordinate regulation of retinoic acid synthesis by pbx genes and fibroblast growth factor signaling by hoxb1b is required for hindbrain patterning and development, 28-41, Copyright (2018) with permission from Elsevier. Full text @ Mech. Dev.