FIGURE

Fig. S3

ID

ZDB-FIG-180417-43

Publication

Shi et al., 2017 - The Retinol Binding Protein Receptor 2 (Rbpr2) is required for Photoreceptor Outer Segment Morphogenesis and Visual Function in Zebrafish

Other Figures

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Fig. S3

ZIRC rbpr2 mutants (rbpr2sa10706) show eye phenotypes consistent with retinol deficiency

A rbpr2 mutant zebrafish line (G>A mutation; rbpr2^sa10706) from the Zebrafish International Resource Center (ZIRC) which affects the essential splice site of exon 5/intron 6, was obtained and analyzed by light microscopy, histology and immunohistochemistry for cones at 5.5 dpf. The resulting eye phenotype observed was similar to the TALEN generated rbpr2 mutant phenotype (rbpr2^musc97) described. Rbpr2^sa10706 mutants showed gross defects, which included: *hydrocephaly; **smaller eyes, ***pericardial edema and ****slight tail curvature.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	stra6l^{sa10706/sa10706}
Observed In:	brain eye pericardium photoreceptor outer segment layer photoreceptor outer segment post-vent region retina photoreceptor outer segment retina layer formation retinal pigmented epithelium
Stage:	Day 5

Phenotype Detail

Acknowledgments

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