Fig. S3
ZIRC rbpr2 mutants (rbpr2sa10706) show eye phenotypes consistent with retinol deficiency
A rbpr2 mutant zebrafish line (G>A mutation; rbpr2sa10706) from the Zebrafish International Resource Center (ZIRC) which affects the essential splice site of exon 5/intron 6, was obtained and analyzed by light microscopy, histology and immunohistochemistry for cones at 5.5 dpf. The resulting eye phenotype observed was similar to the TALEN generated rbpr2 mutant phenotype (rbpr2musc97) described. Rbpr2sa10706 mutants showed gross defects, which included: *hydrocephaly; **smaller eyes, ***pericardial edema and ****slight tail curvature.