FIGURE

Fig. 3

ID

ZDB-FIG-170912-22

Publication

Lamont et al., 2016 - The LIM-homeodomain transcription factor Islet2a promotes angioblast migration

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Fig. 3

Loss of Isl2a interferes with angioblast migration and fli1a expression. (A) qPCR expression of angioblast genes. (B-I) Expression of etsrp/etv2 in wild type (B,D,F,H), isl2^MO (C,E) or isl2a^ca21 mutants (G,I) as seen in dorsal or posterior views. Red bracket denotes expression at posterior of embryo.

Expression Data

Genes:	etsrp fli1 gata1a vegfc
Fish:	TL isl2a^ca21/ca21 TL + MO4-isl2a + MO5-isl2a
Knockdown Reagents:	MO4-isl2a MO5-isl2a
Anatomical Terms:	posterior lateral mesoderm angioblastic mesenchymal cell whole organism
Stage Range:	10-13 somites to Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	isl2a^ca21/ca21 TL + MO4-isl2a + MO5-isl2a
Knockdown Reagents:	MO4-isl2a MO5-isl2a
Observed In:	angioblastic mesenchymal cell posterior lateral mesoderm angioblastic mesenchymal cell whole organism
Stage Range:	10-13 somites to Prim-5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 414, Lamont, R.E., Wu, C.Y., Ryu, J.R., Vu, W., Davari, P., Sobering, R.E., Kennedy, R.M., Munsie, N.M., Childs, S.J., The LIM-homeodomain transcription factor Islet2a promotes angioblast migration, 181-92, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.