FIGURE
Fig. S3
- ID
- ZDB-FIG-160304-28
- Publication
- Ye et al., 2016 - An insulin signaling feedback loop regulates pancreas progenitor cell differentiation during islet development and regeneration
- Other Figures
- All Figure Page
- Back to All Figure Page
Fig. S3
Pancreatic β cell mass normalizes to wild type levels at 96 hpf after continual induction of HOT:dnIRS2. (A-B′′) Merged and single channel confocal projections of 96 hpf HOT:dnIRS2 Cre- control (A-A′′) and HOT:dnIRS2 (B-B′′) islets after heat shock at 10 hpf, 24 hpf, 28 hpf, 32 hpf, 36 hpf, 48 hpf, 56 hpf ,72 hpf and 80 hpf. Ubiquitous induction of dnIRS2- GFP occurs only in the Cre+ embryos. (C) Quantification of β cells in 96 hpf HOT:dnIRS2 Cre-control (n=12) and HOT:dnIRS2 (n=10) islets; β cell mass is indistinguishable between the two conditions. Student’s t-test was used to determine significance in C. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Biology, 409(2), Ye, L., Robertson, M.A., Mastracci, T.L., Anderson, R.M., An insulin signaling feedback loop regulates pancreas progenitor cell differentiation during islet development and regeneration, 354-69, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.