FIGURE

Fig. 10

ID

ZDB-FIG-150325-20

Publication

Mommaerts et al., 2014 - Smoc2 modulates embryonic myelopoiesis during zebrafish development

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Fig. 10

smoc2 morphants do not display cardiovascular defects. Dorsal (A–D: anterior to the top; E–H: anterior to the left) and lateral view (I–R′ anterior to the left) of embryos at 12 ss (A,B,E,F), 20 ss (C,D,G,H), the onset of blood cell circulation (I–P) and 50 hpf (Q,R′). Analysis of the expression pattern of the early cardiac marker nkx2.5 (A–D), the vascular marker fli (E–H), the dorsal aorta marker vegfc (I,J), the marker for all venous and arterial cells flt4 (K,L), the endothelial marker flk1 (M,N) and the arterial marker dll4 (O,P) (n ≥ 14). Q–R′: Visualization of the fli-positive vasculature using the (Tg(fli:eGFP)^y1) reporter fish at 50 hpf.

Expression Data

Genes:	dll4 EGFP fli1 flt4 kdrl nkx2.5 vegfc
Fish:	WT WT + MO4-tp53 + MO5-smoc2 y1Tg y1Tg + MO4-tp53 + MO5-smoc2
Knockdown Reagents:	MO4-tp53 MO5-smoc2
Anatomical Terms:	artery blood vessel dorsal aorta endothelial cell heart primordium vasculature vein
Stage Range:	10-13 somites to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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