FIGURE

Fig. 4

ID

ZDB-FIG-140527-26

Publication

Rydeen et al., 2014 - Cyp26 enzymes are required to balance the cardiac and vascular lineages within the anterior lateral plate mesoderm

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Fig. 4

Loss of Cyp26 enzymes leads to differential shifts in cardiac progenitor markers. (A-B2) Double in situ hybridization of nkx2.5 (red) and etv2 (blue) shows a small gap between expression domains in Cyp26-deficient embryos that is not present in wild-type siblings. (C-D2) Double in situ hybridization with hand2 (blue) and etv2 (red) shows no space between expression domains in wild-type and Cyp26-deficient embryos. A-D are dorsal views with anterior upwards. A2-D2 are dorsal views with anterior leftwards. A2-D2 correspond to boxed areas in A-D, respectively. Arrows indicate the borders between expression domains.

Expression Data

Genes:	etsrp hand2 nkx2.5
Fish:	WT WT + MO1-cyp26c1 + MO4-cyp26a1 + MO5-cyp26a1
Knockdown Reagents:	MO1-cyp26c1 MO4-cyp26a1 MO5-cyp26a1
Anatomical Terms:	anterior lateral plate mesoderm anterior lateral plate mesoderm cardiovascular system anterior lateral plate mesoderm heart primordium cardiovascular system heart primordium
Stage:	5-9 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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