FIGURE

Fig. 4

ID

ZDB-FIG-140428-19

Publication

Zhao et al., 2014 - Notch signaling regulates cardiomyocyte proliferation during zebrafish heart regeneration

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Fig. 4

Evidence for regeneration of coronary endothelium in Notch-inhibited hearts. (A and B) Representative cardiac sections from heat shocked control (CTRL) (A) and Tg(hsp70:DN-MAML) (B) animals carrying the Tg(kdrl:mCherry) endothelial reporter at 30 dpa. (Insets) Higher magnification views of boxed regions in A and B. Whereas control animals regenerated mCherry+ endocardium and coronary vessels, Tg(hsp70:DN-MAML) hearts harbored mCherry+ endothelial tubes in the nonregenerated region of the heart. The myocardium is autofluorescent in A and B. Fourteen of 14 control and 11 of 11 Tg(hsp70:DN-MAML) hearts demonstrated these phenotypes.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA