FIGURE

Fig. S1

ID

ZDB-FIG-140211-19

Publication

Dyer et al., 2014 - A bi-modal function of Wnt signalling directs an FGF activity gradient to spatially regulate neuronal differentiation in the midbrain

Other Figures

All Figure Page

Back to All Figure Page

Fig. S1

Characterisation of MTN neuronal development. DiI labelling (A,D) of jaw muscles and GFP (B,E) in Tg[dlx5a/6a:egfp] 5 dpf larvae reveals that a proportion of MTN neurons (arrowheads) co-express GFP and are larger than adjacent tectal GFP+ neurons (arrow, C,F). At 24 hpf many huc /elavl3 expressing progenitor cells are present along the A-P extent of the midbrain (G). In contrast drg11 expressing MTN (arrowheads) are restricted to the pax7 expressing midbrain (I) in comparison to nTPC neurons present in the pax6+ forebrain (H). In Tg[elavl3:gfp] embryos at 24 hpf MTN and nTPC neurons are GFP+ and express drg11 (J), Isl1 (K) and HuC protein (L). Scale bars 100 μm (A-C,G-K) 50μm (L) 20μm (D-F).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development