FIGURE

Fig. 6

ID

ZDB-FIG-130802-6

Publication

Wang et al., 2013 - Subtractive phage display technology identifies zebrafish marcksb that is required for gastrulation

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Fig. 6

Zebrafish marcksb is required for gastrulation movements through regulation of cell membrane protrusion and F-actin alignment. A: pEGFP injected embryos; B: pEGFP and marcksb MO co-injected embryos; C: pEGFP-marcksb injected embryos; D: pEGFP-marcksb and marcksb MO co-injected embryos; E: ntl, dlx3 and hgg1 labeled wildtype embryos; F: ntl, dlx3 and hgg1 labeled marcksb MO injected embryos; G: visualization of membrane protrusion in wildtype embryos; H: visualization of membrane protrusion in marcksb MO injected embryos; I: visualization of F-actin alignment in wildtype embryos; J: visualization of F-actin alignment in marcksb MO injected embryos.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-marcksb
Knockdown Reagent:	MO1-marcksb
Observed In:	cell cell filamentous actin cell filopodium convergent extension involved in gastrulation gastrulation
Stage Range:	75%-epiboly to 1-4 somites

Phenotype Detail

Acknowledgments

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Reprinted from Gene, 521(1), Wang, Y.W., Wei, C.Y., Dai, H.P., Zhu, Z.Y., and Sun, Y.H., Subtractive phage display technology identifies zebrafish marcksb that is required for gastrulation, 69-77, Copyright (2013) with permission from Elsevier. Full text @ Gene