FIGURE

Fig. 1

ID

ZDB-FIG-130318-10

Publication

Lu et al., 2013 - Failure in closure of the anterior neural tube causes left isomerization of the zebrafish epithalamus

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

flh is expressed in embryos with an open neural tube. In (A, E) WT and (B, F) sqt mutant embryos with closed neural tubes, the pineal precursors (p, white arrowheads) form a single, oval domain that spans the dorsal midline (dotted lines) separating the left (L) and right (R) sides of the epithalamus. (C) In sqt embryos with mild open neural tube defects, the pineal precursors still span the dorsal midline of the brain, but the pineal anlage is elongated along the left–right axis. (D, G, H) In sqt and cyc; sqt embryos with a severe open neural tube phenotypes, the pineal precursors are present in two divided domains on the left and right sides of the brain. Dorsal views of the epithalamus in (A–D) live or (E–H) fixed embryos, anterior to the top. Scale bar=20 μm.

Expression Data

Genes:	EGFP noto
Fish:	WT ndr1^cz35/cz35 c162Tg ndr1^cz35/cz35; c162Tg ndr2^m294/m294; ndr1^cz35/cz35 ndr2^m294/m294; ndr1^cz35/cz35; c162Tg
Anatomical Term:	pinealocyte
Stage Range:	26+ somites to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ndr1^cz35/cz35 ndr1^cz35/cz35; c162Tg ndr2^m294/m294; ndr1^cz35/cz35 ndr2^m294/m294; ndr1^cz35/cz35; c162Tg
Observed In:	epiphysis neural tube
Stage Range:	26+ somites to Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 374(2), Lu, P.N., Lund, C., Khuansuwan, S., Schumann, A., Harney-Tolo, M., Gamse, J.T., and Liang, J.O., Failure in closure of the anterior neural tube causes left isomerization of the zebrafish epithalamus, 333-344, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.