FIGURE

Fig. S11

ID

ZDB-FIG-110811-12

Publication

Matsui et al., 2011 - Canopy1, a positive feedback regulator of FGF signaling, controls progenitor cell clustering during Kupffer's vesicle organogenesis

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Fig. S11

DFC-specific knockdown of tbx16 or cdh1 results in the broken-up DFC phenotype. (A-C) Dorsal view of sox32 expression in uninjected (A), DFC^tbx16-MO (B) or DFC^chd1-MO (C) embryos at 65% epiboly stage. Dorsal view, anterior to the top. Scale bar: 200 μm. (D) Percentages of normal or broken-up DFCs were scored using the sox32 expression pattern in uninjected (n = 64), DFC^tbx16-MO (n = 55), DFC^cdh1-MO (n = 69) yolk^tbx16-MO (n = 61) and yolk^cdh1-MO (n = 65) embryos. Statistically significant (P < 0.05) differences could be seen in uninjected versus DFC^tbx16-MO (P = 1.68 x 10^-4) and DFC^cdh1-MO (P = 1.17 x 10^-8), but not between uninjected and yolk^tbx16-MO (P = 1.00) or yolk^cdh1-MO (P = 1.00).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA