FIGURE

Fig. S2

ID

ZDB-FIG-110804-83

Publication

Matsui et al., 2011 - Canopy1, a positive feedback regulator of FGF signaling, controls progenitor cell clustering during Kupffer's vesicle organogenesis

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Fig. S2

A positive control loop between Cnpy1 and FGF signaling is established in DFCs. (A-C) dp-Erk staining in uninjected (A), cnpy1-MO-injected (B) or DFC^cnpy1-MO-injected (C) embryos at 60% epiboly stage. Scale bar: 200 μm. (D, E) dp-Erk staining in control-MO-injected (D) or cnpy1-MO-injected (E) Tg[sox17:GFP] embryos at 60% epiboly stage. Scale bar: 20 μm. dp-Erk signals (red) were down-regulated in GFP-positive DFCs (green). (F, G) cnpy1 (purple) and GFP (red) expression in control-MO-injected (F) or fgf8-MO-injected (G) Tg[sox17:GFP] embryos at 60% epiboly stage. Scale bar: 200 μm. Dotted lines mark the outlines of DFC populations.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA