ZFIN Image: Matsui et al., 2011, Fig. S11

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Figure Caption

Fig. S11

DFC-specific knockdown of tbx16 or cdh1 results in the broken-up DFC phenotype. (A-C) Dorsal view of sox32 expression in uninjected (A), DFC^tbx16-MO (B) or DFC^chd1-MO (C) embryos at 65% epiboly stage. Dorsal view, anterior to the top. Scale bar: 200 μm. (D) Percentages of normal or broken-up DFCs were scored using the sox32 expression pattern in uninjected (n = 64), DFC^tbx16-MO (n = 55), DFC^cdh1-MO (n = 69) yolk^tbx16-MO (n = 61) and yolk^cdh1-MO (n = 65) embryos. Statistically significant (P < 0.05) differences could be seen in uninjected versus DFC^tbx16-MO (P = 1.68 x 10^-4) and DFC^cdh1-MO (P = 1.17 x 10^-8), but not between uninjected and yolk^tbx16-MO (P = 1.00) or yolk^cdh1-MO (P = 1.00).

Acknowledgments

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