FIGURE

Fig. S4

ID

ZDB-FIG-110207-51

Publication

Wang et al., 2011 - Genetic inducible fate mapping in larval zebrafish reveals origins of adult insulin-producing {beta}-cells

Other Figures

All Figure Page

Back to All Figure Page

Fig. S4

Cre-responder line capable of reporting on exocrine fate mapping in 5 dpf larvae. Confocal images of single optic sections of micro-dissected pancreata from β-actin:eGFP-F2A-cre^ERT2; β-actin:loxP-stop-loxP-hmgb1-mCherry 5dpf larvae. (A,B) Following 4OHT addition at 56 hpf, cells within the pancreas parenchyma are labeled with the lineage tracer Hmgb1-mCherry. (A) Counterstaining for nuclei in blue indicates number of cells in field. Red nuclei indicate lineage-traced cells. (B) Merged red and bright-field images show that these labeled or lineage-traced cells include zymogen granule filled acinar cells of the exocrine pancreas. (C,D) Without 4OHT treatment, no labeling is detected.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development