FIGURE

Fig. 2

ID

ZDB-FIG-101118-2

Publication

Chitramuthu et al., 2010 - Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of Survival motor neuron 1

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Fig. 2

Colocalization of zfPGRN-A and znp1 immunoreactivity in Primary motor neurons at 27 hpf. Lateral views (anterior- left; dorsal- top) of whole-mount embryos labelled with zfPGRN-A (A, D) and znp1 mAb (B, E) at 27 hpf. Embryos show zfPGRN-A expression in the developing eye, tectum and hindbrain (A); Spinal Cord, Somite boundaries and motor neurons (D); znp1 expression in the eye, hindbrain, Spinal Cord and motor neurons (B and E). Merged images show co-localization of zfPGRN-A and znp1 (C, F). Abbreviations: T, Tectum; E, Eye; MHB, Mid-Brain Hindbrain Boundary; SB, Somite boundary; MN, Motoneurons.; SC, Spinal cord. Images were captured at 20 × magnification. Scale Bar = 50 μm.

Expression Data

Gene:	grna
Antibodies:	Ab1-grna znp-1
Fish:	WT
Anatomical Terms:	hindbrain optic cup optic tectum primary motor neuron axon spinal cord motor neuron vertical myoseptum
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Mol. Neurodegener.