FIGURE

Fig. 4

ID

ZDB-FIG-100806-82

Publication

Herrgen et al., 2010 - Intercellular Coupling Regulates the Period of the Segmentation Clock

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Fig. 4

Determination of Segmentation Clock Collective Period from Oscillating Gene Expression Patterns

(A) In situ hybridization: deltaC and isl1 (interneurons and Rohon-Beard neurons, n) in representative wild-type and mib embryos. The scale bar represents 50 μm.

(B) Measurements of normalized gene expression wavelength λ and position x; wild-type is black and mib is pink. Data points: n (wt) = 65, 28 embryos, n (mib) = 70, 28 embryos, two independent trials. Curves indicate fit of Equation 3 to data (Experimental Procedures).

(C) Values of frequency profile decay length ρ, and normalized segment length s parameters from the fit to the data. Error bars show 95% CI from bootstrap analysis (Supplemental Experimental Procedures 2.2.5). ^**p < 0.001, Student′s t test.

Expression Data

Genes:	dlc isl1a
Fish:	WT mib1^ta52b/ta52b
Anatomical Terms:	interneuron Rohon-Beard neuron somite
Stage:	1-4 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mib1^ta52b/ta52b
Observed In:	somite somitogenesis
Stage:	1-4 somites

Phenotype Detail

Acknowledgments

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