FIGURE

Fig. 3

ID

ZDB-FIG-100806-81

Publication

Herrgen et al., 2010 - Intercellular Coupling Regulates the Period of the Segmentation Clock

Other Figures

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Fig. 3

Segment Length Increases after Reduction in Delta-Notch Coupling

(A) Somites of six-somite-stage live embryos. Bars indicate formed somite boundaries; arrowheads indicate forming boundaries. Dorsal view is anterior to top. The scale bar represents 25 μm.

(B) Somite lengths (mean ± 95% CI), n ≥ 40 total embryos per experimental condition, except n = 14 for somite five in aei/deltaD, six independent trials per experimental condition. For control population, the largest CI detected is displayed.

(C) In situ hybridization of mespb (arrowheads) and isl1 (interneurons, Rohon-Beard neurons, n). The scale bar represents 50 μm.

(D) Box-and-whisker plots of segment length, n ≥ 40 total embryos, more than three independent trials per experimental condition. ^*p < 0.01, ^**p < 0.001, Student′s t test. Figure S3 shows that the position of the arrest front in the PSM is unchanged in the conditions with increased segment length. The central box covers the interquartile range with the mean indicated by the small square and the median by the line within the box. The whiskers extend to the 5^th and 95^th percentiles, and small bars depict the most extreme values.

Expression Data

Genes:	isl1a mespba
Fish:	WT mib1^ta52b/ta52b
Anatomical Terms:	interneuron Rohon-Beard neuron somite
Stage:	5-9 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	dld^tr233/tr233 mib1^ta52b/ta52b notch1a^tp37/tp37
Observed In:	somite 2 somite 3 somite 4 somite 5 somitogenesis
Stage:	5-9 somites

Phenotype Detail

Acknowledgments

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