FIGURE

Fig. 4

ID

ZDB-FIG-090821-3

Publication

Petko et al., 2009 - Proteomic and functional analysis of NCS-1 binding proteins reveals novel signaling pathways required for inner ear development in zebrafish

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Fig. 4

Phenotypes of embryos co-injected with subeffective doses of NBP MOs. Bar graph depicts percent of fish at 48 hpf or 72 hpf that displayed normal epithelial protrusions or semicircular canal hub formation, abnormal epithelial protrusions or semicircular canal hub formation, or absence of epithelial protrusions. Embryos were injected with 0.5 ng of ncs-1a-ATG MO alone, 0.5 ng of arf1-UTR MO alone, or 2 ng of pi4kβ-ATG MO alone. Alternatively, embryos were co-injected with 0.5 ng of ncs-1a-ATG MO plus 0.5 ng of arf1-UTR MO, 0.5 ng of ncs-1a-ATG MO plus 2 ng of pi4kβ-ATG MO, or 0.5 ng arf1-UTR plus 2 ng pi4kβ-ATG MO. The number of fish assayed for each treatment is displayed above the bars.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-ncs1a + MO1-pi4kb WT + MO1-ncs1a + MO2-arf1 WT + MO1-pi4kb + MO2-arf1
Knockdown Reagents:	MO1-ncs1a MO1-pi4kb MO2-arf1
Observed In:	semicircular canal development
Stage Range:	Long-pec to Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Neurosci.