FIGURE

Fig. 6

ID

ZDB-FIG-090817-14

Publication

McMahon et al., 2009 - Lmx1b is essential for survival of periocular mesenchymal cells and influences Fgf-mediated retinal patterning in zebrafish

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Fig. 6

Lmx1b functions cell-autonomously in development of periocular mesenchymal cells. (A) Bright field and fluorescent images of control MO and lmx1bdMO eyes showing foxD3:GFP-positive periocular mesenchymal cells. (B) Ocular region (outlined by white dots) of 30 hpf mosaic embryos showing wild-type or lmx1bdMO morphant donors. All donor cell nuclei are positive for H2A:mCherry (red), while a subset of periocular cells are positive for foxD3:GFP (green). (C) Average number ± Standard Error of the Mean for total H2A:mCherry and foxD3:GFP-positive donor periocular cells from mosaic embryos. Percent of total periocular cells that were foxD3-positive is shown in the right-most column. For each condition, donor cells from n = 12 independent eyes were scored.

Expression Data

Gene:	GFP
Fish:	zf15Tg zf15Tg + MO2-lmx1bb + MO3-lmx1ba
Knockdown Reagents:	MO2-lmx1bb MO3-lmx1ba
Anatomical Term:	periocular mesenchyme
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 332(2), McMahon, C., Gestri, G., Wilson, S.W., and Link, B.A., Lmx1b is essential for survival of periocular mesenchymal cells and influences Fgf-mediated retinal patterning in zebrafish, 287-298, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.